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LNS - Laboratoire National de Santé

LNS - Laboratoire National de Santé

Clinical Laboratory Geneticist / Cytogeneticist / Biologist (m/f)

Dudelange, LUSur siteCDITemps plein

Publié 5 août 2026

Cet emploi est publié en EN

Clinical Laboratory Geneticist/Cytogeneticist/Biologist (m/f) ref°543


TYPE DE CONTRAT : CDI - temps plein

We are currently looking for a Clinical Laboratory Geneticist/Cytogeneticist/Biologist (m/f) for our department “National Center of Genetics” for a permanent position on a full-time basis (40h/week).


RESPONSIBILITIES


  • Participating in the daily management of the laboratory;
  • Participating in a regular rotation between the hematooncogenetics and constitutional cytogenetics activities within the Hematooncogenetics and Cytogenetics Unit;
  • Performing genetic diagnostics, interpretation and reporting in constitutional cytogenetics (pre- und postnatal);
  • Performing cytogenetic and molecular cytogenetic analyses, including metaphase evaluation, FISH and Bionano, and preparing comprehensive, integrated diagnostic reports for hematological malignancies by consolidating these findings with bone marrow morphology (myelogram), flow cytometry, molecular genetics, and other relevant laboratory and clinical results;
  • Participate in the development of research projects and applying scientific knowledge in expanding the diagnostic and research portfolio of the NCG;
  • Seek funding from national (FNR) and international funding bodies including writing scientific proposals;
  • Optimizing existing methods and developing new ones;
  • Planning, interpretation and reporting of molecular genetic examinations
  • Participation in the development and maintenance of a quality system based on (ISO 15189);
  • Participating in external quality control trials;
  • Training and supervision of the technicians;
  • Participating to clinical staff meeting at National Center of Genetics and in other multidisciplinary meeting.
  • Communicate cytogenetic findings to referring physicians when appropriate.
  • Keep up to date with the latest scientific, technological, and clinical developments in constitutional and hemato-oncology cytogenetics.

PROFILE


  • PhD/Master sciences in Genetics or other similar qualification in clinical genetics;
  • Several years of experience in a diagnostic cytogenetics laboratory, including independent interpretation and reporting in both constitutional cytogenetics (pre- and postnatal) and cancer cytogenetics/hematological neoplasia, as well as experience in preparing integrated hemato-oncology reports combining cytogenetic, morphological, immunophenotypic, molecular, and relevant clinical findings, is mandatory;
  • Knowledge of specific chromosomal aberrations in leukemia and their detection also on preparations with metaphases that are very difficult to analyze;
  • Application of different methods of in situ hybridization (interphase nucleus diagnostics, metaphase analysis with directly labeled probes);
  • Experience in the interpretation of Bionano datasets would be desirable;
  • Willingness to take on responsibility;
  • Ability to work in a team, resilience, flexibility, ability to work under pressure and high commitment characterize you;
  • You have a strong interest in genetic/medical issues and an exceptionally high level of motivation;
  • Willingness to establish new methods for diagnostic application;
  • Experience in quality management (ISO15189) is an advantage;
  • Good knowledge of MS-Office, especially Excel. Experience with Laboratory Information and Management Systems (LIMS) and bioinformatics tools is appreciated;
  • Advanced English knowledge in spoken and written is required; knowledge of German is an advantage.


If you meet the above profile and wish to apply, please submit your application (CV and Cover letter) via our website. Your application will be treated confidentiality.


At the final stages of the recruitment process, the successful candidate will be asked to provide supporting documentation such as, copies of diplomas and certificates of employment. An official criminal record (bulletin no.3) will also be required for consultation purpose.

Aperçu du poste

Type de poste

Temps plein

E-mail

Valentina.Fiorino@lns.etat.lu

Compétences requises

Fluorescence in situ hybridization (FISH)Metaphase chromosome analysis / metaphase evaluationBionano dataset interpretationIntegrated hemato‑oncology diagnostic reporting (consolidating cytogenetic, morphology, flow cytometry, molecular and clinical data)Constitutional cytogenetic diagnostics (pre‑ and postnatal)Interpretation and reporting of molecular genetic examinationsDetection and interpretation of chromosomal aberrations in leukemia, including analysis of difficult metaphasesDevelopment and optimization of laboratory methods and assaysQuality management and implementation of ISO 15189Participation in external quality control trials (EQA)Training, supervision and mentoring of laboratory techniciansGrant writing and developing research project proposals for national and international fundingExperience with Laboratory Information Management Systems (LIMS) and bioinformatics toolsAdvanced English communication (spoken and written) for clinical/scientific contextsProficiency with MS Office, especially Excel

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